| Description | SCH-39370 is a potent and specific neutral metalloendopeptidase (NEP) inhibitor. |
| Synonyms | SCH 39370 |
| molecular weight | 414.45 |
| Molecular formula | C22H26N2O6 |
| CAS | 115406-23-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Chappell MC, Allred AJ, Ferrario CM. Pathways of angiotensin-(1-7) metabolism in the kidney. Nephrol Dial Transplant. 2001;16 Suppl 1:22-6. Review. PubMed PMID: 11369816. 2. Iyer SN, Averill DB, Chappell MC, Yamada K, Allred AJ, Ferrario CM. Contribution of angiotensin-(1-7) to blood pressure regulation in salt-depleted hypertensive rats. Hypertension. 2000 Sep;36(3):417-22. PubMed PMID: 10988275. 3. Chappell MC, Gomez MN, Pirro NT, Ferrario CM. Release of angiotensin-(1-7) from the rat hindlimb: influence of angiotensin-converting enzyme inhibition. Hypertension. 2000 Jan;35(1 Pt 2):348-52. PubMed PMID: 10642323. 4. Hämäläinen KM, Ranta VP, Auriola S, Urtti A. Enzymatic and permeation barrier of [D-Ala(2)]-Met-enkephalinamide in the anterior membranes of the albino rabbit eye. Eur J Pharm Sci. 2000 Jan;9(3):265-70. PubMed PMID: 10594383. |