| Description | SARS-CoV-IN-1 is an effective SARS-CoV replication inhibitor(EC50 of 4.9 μM in Vero cells). |
| In vitro | In vitro growth of Plasmodium falciparum inhibited by SARS-CoV-IN-1 far better than Chloroquine (CQ) . |
| Target activity | SARS-CoV (Vero cells):4.9 μM(EC50) , P. falciparum (W2):133.2 nM , P. falciparum (W2):459.1 nM, P. falciparum (3D7):15.4 nM , P. falciparum (3D7):IC90: 25.7 nM |
| molecular weight | 449.76 |
| Molecular formula | C23H24ClFeN3O |
| CAS | 888958-25-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Biot C, et al. Design and synthesis of hydroxyferroquine derivatives with antimalarial and antiviral activities. J Med Chem. 2006 May 4;49(9):2845-9. |