| Description | SARS-CoV-2 nsp3-IN-2 is a SARS-CoV-2 nsp3 macrodomain (Mac1) inhibitor with IC 50 value of 180 μM. SARS-CoV-2 nsp3 macrodomain is an ADP-ribosylhydrolase that is critical for coronavirus replication and pathogenesis. SARS-CoV-2 nsp3-IN-2 is a small molecule chemical probe that can be used for the viral research[1]. |
| In vitro | SARS-CoV-2 nsp3-IN-2 shows weak potency against Mac1 in an ADP-ribose binding AlphaScreen assay with IC 50 value of 180 μM [1]. |
| molecular weight | 220.23 |
| Molecular formula | C10H12N4O2 |
| CAS | 2038858-11-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |