Description | SARS-CoV-2 3CLpro-IN-20 is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 0.43 μM,).SARS-CoV-2 3CLpro-IN-20 has potential antiviral activity. |
Target activity | 3CLpro (SARS CoV-2):0.43 μM |
molecular weight | 366.21 |
Molecular formula | C19H12BrNO2 |
CAS | 878985-00-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 3.66 mg/mL (10 mM), Sonication is recommended. |
References | 1. Bao HL, et al. Design and synthesis of isatin derivatives as effective SARS-CoV-2 3CL protease inhibitors. Chem Biol Drug Des. 2023 Aug 10. |