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Sarcophine

CAS No.: 55038-27-2

Sarcophine is a natural cembranoid from the Red Sea soft coral Sarcophyton glaucum.
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Description Sarcophine is a natural cembranoid from the Red Sea soft coral Sarcophyton glaucum.
Synonyms Sarcophin, Sarcophin A
molecular weight 316.441
Molecular formula C20H28O3
CAS 55038-27-2
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Szymanski PT, Ahmed SA, Radwan MM, Khalifa SI, Fahmy H. Evaluation of the anti-melanoma activities of sarcophine, (+)-7alpha,8beta-dihydroxydeepoxysarcophine and sarcophytolide from the Red Sea soft coral Sarcophyton glaucum. Nat Prod Commun. 2014 Feb;9(2):151-4. PubMed PMID: 24689276. 2. Szymanski PT, Ahmed SA, Khalifa S, Tokuda H, Ichiishi E, Iida A, Suzuki N, Fahmy H. Chemopreventive effect of sarcophine-diol on NOR-1-induced TPA-promoted skin carcinogenesis in female HOS:HR-1 mice. Nat Prod Commun. 2013 Feb;8(2):153-4. PubMed PMID: 23513714. 3. Hassan HM, Sallam AA, Mohammed R, Hifnawy MS, Youssef DT, El Sayed KA. Semisynthetic analogues of the marine cembranoid sarcophine as prostate and breast cancer migration inhibitors. Bioorg Med Chem. 2011 Aug 15;19(16):4928-34. doi: 10.1016/j.bmc.2011.06.060. Epub 2011 Jun 28. PubMed PMID: 21775154. 4. Szymanski PT, Kuppast B, Ahmed SA, Khalifa S, Fahmy H. Sarcophine-diol, a skin cancer chemopreventive agent, inhibits proliferation and stimulates apoptosis in mouse melanoma B₁₆F₁₀ cell line. Mar Drugs. 2012 Jan;10(1):1-19. doi: 10.3390/md10010001. Epub 2011 Dec 22. PubMed PMID: 22363217; PubMed Central PMCID: PMC3280529.