| Description | SAHA chloroalkane T1 is a novel compound formed by combining Vorinostat (SAHA) with a chloroalkane capture tag, referred to as T1. This innovative approach involves tethering the SAHA molecule with the T1 tag, resulting in the formation of SAHA chloroalkane T1. |
| In vitro | in K-562 cells,SAHA chloroalkane T1 minimally affects SAHA potency, allowing binding interactions with the targets to occur under conditions relevant to the desired cellular phenotype. |
| molecular weight | 719.26 |
| Molecular formula | C33H55ClN4O11 |
| CAS | 1613617-05-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 125 mg/mL (173.79 mM), Sonication is recommended. |
| References | 1. Ohana RF, et al. Deciphering the Cellular Targets of Bioactive Compounds Using a Chloroalkane Capture Tag. ACS Chem Biol. 2015 Oct 16;10(10):2316-24. |