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Sacubitril-(2S,4S)-Isomer

CAS No.:

Sacubitril-(2S,4S)-Isomer ((2S,4S)-Sacubitril) is the isomer of Sacubitril which is a neprilysin inhibitor.
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Description Sacubitril-(2S,4S)-Isomer ((2S,4S)-Sacubitril) is the isomer of Sacubitril which is a neprilysin inhibitor.
Synonyms (2S,4S)-Sacubitril, LCZ 696杂质C
molecular weight 430.49
Molecular formula C24H28NO5 1/2Ca
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: 50 mg/mL (116.15 mM)
References 1. Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9.