Description | Sacubitril-(2S,4S)-Isomer ((2S,4S)-Sacubitril) is the isomer of Sacubitril which is a neprilysin inhibitor. |
Synonyms | (2S,4S)-Sacubitril, LCZ 696杂质C |
molecular weight | 430.49 |
Molecular formula | C24H28NO5 1/2Ca |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility | DMSO: 50 mg/mL (116.15 mM) |
References | 1. Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9. |