Description | Sabcomeline, a potent and functionally selective partial agonist at muscarinic M1 receptors, enhances cognition and is utilized in Alzheimer's disease research [1] [2]. |
In vitro | LCS3 (5 nM-10 µM ; 96 h) effectively inhibits lung cancer cell lines, while non-transformed lung cells show no signs of inhibition.[1] LCS3 (3 µM ; 3, 6, and 12 h) induces ROS and NRF2 pathway activation in sensitive lung adenocarcinoma (LUAD) cells.[1] LCS3 (3 µM ; 96 h) selectively kills lung adenocarcinoma (LUAD) cell lines, in part through the induction of apoptosis.[1] |
Synonyms | SB-202026, SB-202026 ; Memric, Memric |
molecular weight | 193.25 |
Molecular formula | C10H15N3O |
CAS | 159912-53-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |