| Description | S-Methylglutathione (S-Methyl glutathione) is an S-substituted glutathione, an inhibitor of the 1-chloro-2,4-dinitrobenzene coupling catalyzed by transferase A and an XOCl scavenger.S-Methylglutathione inhibits glyoxalase 1 (glyoxalase 1), which induces the development of the glyoxalase 1 enzyme. S-Methylglutathione inhibits glyoxalase 1 (glyoxalase 1) and induces the formation of hydroid tentacle balls. |
| Synonyms | Glutathione S-methyl ester, Glutathione ester, S-Methyl glutathione |
| molecular weight | 321.35 |
| Molecular formula | C11H19N3O6S |
| CAS | 2922-56-7 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: 15 mg/mL (46.68 mM), Sonication is recommended. |
| References | 1. Terwilliger TC,et al. S-methyl glutathione synthesis is catalyzed by the cheR methyltransferase in Escherichia coli. J Bacteriol. 1986 Mar;165(3):958-63. 2. Manabe Y, et al. Suppression of S-methylglutathione-induced tentacle ball formation by peptides and nullification of the suppression by TGF-beta in Hydra. Chem Senses. 2000 Apr;25(2):173-80. 3. Bobrowski K,et al. Sulfur radical cation-peptide bond complex in the one-electron oxidation of S-methylglutathione. J Am Chem Soc. 2007 Jul 25;129(29):9236-45. 4. Müller M,et al. High-performance liquid chromatography/fluorescence detection of S-methylglutathione formed by glutathione-S-transferase T1 in vitro. Arch Toxicol. 2001 Feb;74(12):760-7. |