| Description | S-Methoprene (ZR2458) is an analog of juvenile hormone and can be used as an insecticide. S-Methoprene alters redox activity of cytochrome oxidase and induces male sex differentiation. |
| Synonyms | ZR2458, ZR 2458, ZR-2458, (+)-Methoprene, Preco |
| molecular weight | 310.47 |
| Molecular formula | C19H34O3 |
| CAS | 65733-16-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 95 mg/mL (305.99 mM), Sonication is recommended. |
| References | 1. Dhopeshwarkar AS, Nicholson RA. Benzophenanthridine alkaloid, piperonyl butoxide and (S)-methoprene action at the cannabinoid-1 receptor (CB1-receptor) pathway of mouse brain: Interference with [(3)H]CP55940 and [(3)H]SR141716A binding and modification of WIN55212-2-dependent inhibition of synaptosomal l-glutamate release. Eur J Pharmacol. 2014 Jan 15;723:431-41. 2. Dryden MW, et al. Evaluation and comparison of a flumethrin-imidacloprid collar and repeated monthly treatments of fipronil/(s)-methoprene to control flea, Ctenocephalides f. felis, infestations on cats for eight months. Parasit Vectors. 2016 May 17;9(1):287. 3. Knaus M, et al. Efficacy of a novel topical fipronil, (S)-methoprene, eprinomectin and praziquantel combination against naturally acquired intestinal nematode and cestode infections in cats. Vet Parasitol. 2014 Apr 28;202(1-2):18-25. 4. Adnan SM, et al. Accelerated Sexual Maturation in Methoprene-Treated Sterile and Fertile Male Queensland Fruit Flies (Diptera: Tephritidae), and Mosquito Larvicide as an Economical and Effective Source of Methoprene. J Econ Entomol. 2019 Dec 9;112(6):2842-2849. |