| Description | (S)-(+)-Ibuprofen D3 is a deuterium labeled (S)-(+)-Ibuprofen. (S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen ,it is an inhibitor of COX-1 and COX-2 activity (IC50s of 2.1 μM and 1.6 μM). |
| Target activity | COX-2:1.6 μM, COX-1:2.1 μM |
| Synonyms | (S)-Ibuprofen D3 |
| molecular weight | 209.3 |
| Molecular formula | C13H18O2 |
| CAS | 1329643-44-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Evans AM, et al. Comparative pharmacology of S(+)-ibuprofen and (RS)-ibuprofen. Clin Rheumatol. 2001 Nov;20 Suppl 1:S9-14. 2. Xu HR, et al. The effect of CYP2C19 activity on pharmacokinetics of lansoprazole and its active metabolites in healthy subjects. Pharm Biol. 2010 Aug;48(8):947-52. |