| Description | (S)-AMG-510 是 AMG-510 的 S型化合物，是 KRAS G12C 的强效共价抑制剂，具有潜在的抗肿瘤活性。 |
| molecular weight | 560.59 |
| Molecular formula | C30H30F2N6O3 |
| CAS | 2252403-56-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 5.61 mg/mL (10 mM) |
| References | 1. Canon J , Rex K , Saiki A Y , et al. The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity[J]. Nature, 2019, 575(7781). |