Description | RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies. |
Target activity | Kv2.2:50 nM |
molecular weight | 392.47 |
Molecular formula | C21H20N4O2S |
CAS | 1393748-80-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 60 mg/ml (152.88 mM) |
References | 1. Herrington J, et al. Identification of novel and selective Kv2 channel inhibitors. Mol Pharmacol. 2011 Dec;80(6):959-64. |