| Description | RUVBL1/2 ATPase-IN-1 is an effective RUVBL1/2 ATPase inhibitor with IC50 values of 6.0 and 7.7 μM, respectively. RUVBL1/2 ATPase-IN-1 can be used in cancer disease studies. |
| Target activity | RUVBL1:6.0 μM, RUVBL2:7.7 μM |
| molecular weight | 507.55 |
| Molecular formula | C28H28F3N5O |
| CAS | 423128-55-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 8 mg/mL (15.76 mM), Sonication and heating to 60℃ are recommended. |
| References | 1. Zhang G, et al. Discovery of small-molecule inhibitors of RUVBL1/2 ATPase. Bioorg Med Chem. 2022;62:116726. |