| Description | Rusalatide acetate (TP508 amide acetate), a regenerated peptide, alleviates radiation-induced gastrointestinal injury by activating stem cells and protecting recess integrity. |
| In vitro | Rusalatide(TP508)是一种由23个氨基酸组成的多肽,代表了人类凝血酶原中的508至530个氨基酸。它被确认为凝血酶与成纤维细胞表面部分凝血酶受体进行高亲和力结合的关键域,这种作用被认为是启动组织修复的关键步骤[1]。 |
| Synonyms | Rusalatide acetate, TP508 amide acetate |
| molecular weight | 2371.5 |
| Molecular formula | C99H151N29O37S |
| CAS | 875455-82-6 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: Soluble |
| References | 1. Kantara C, et al. Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity. Lab Invest. 2015 Nov;95(11):1222-33. |