| Description | Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteria |
| In vivo | Rifamycin S和rifabutin能与大鼠肝微粒体发生相互作用，进行redox-cycling反应，在存在铁络合物时进一步产生羟基自由基[1]。 |
| molecular weight | 695.75 |
| Molecular formula | C37H45NO12 |
| CAS | 13553-79-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (71.86 mM), Sonication is recommended. |
| References | 1. Rao DN, et al. A comparative study of the redox-cycling of a quinone (rifamycin S) and a quinonimine (rifabutin) antibiotic by rat liver microsomes. Free Radic Biol Med. 1997;22(3):439-46. 2. Huang H, et al. Rifamycin S and its geometric isomer produced by a newly found actinomycete, Micromonospora rifamycinica. Antonie Van Leeuwenhoek. 2009 Feb;95(2):143-8. |