PeptideDB

Ridaifen-B

CAS No.: 886465-70-9

Ridaifen-B, a tamoxifen derivative, works by inducing independent autophagy of Bcl-2, without estrogen receptor involvem
Sales Email:peptidedb@qq.com

This product is for research use only, not for human use. We do not sell to patients.

Description Ridaifen-B, a tamoxifen derivative, works by inducing independent autophagy of Bcl-2, without estrogen receptor involvement.
Synonyms RidaifenB
molecular weight 510.71
Molecular formula C34H42N2O2
CAS 886465-70-9
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
References 1. Nagahara Y, Takeyoshi M, Sakemoto S, Shiina I, Nakata K, Fujimori K, Wang Y, Umeda E, Watanabe C, Uetake S, Yamori T, Dan S, Yoshimi Y, Shinomiya T, Ikekita M. Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement. Biochem Biophys Res Commun. 2013 Jun 14;435(4):657-63. doi: 10.1016/j.bbrc.2013.05.040. Epub 2013 May 18. PubMed PMID: 23688426. 2. Tsukuda S, Kusayanagi T, Umeda E, Watanabe C, Tosaki YT, Kamisuki S, Takeuchi T, Takakusagi Y, Shiina I, Sugawara F. Ridaifen B, a tamoxifen derivative, directly binds to Grb10 interacting GYF protein 2. Bioorg Med Chem. 2013 Jan 1;21(1):311-20. doi: 10.1016/j.bmc.2012.10.037. Epub 2012 Oct 29. PubMed PMID: 23199482. 3. Nagahara Y, Shiina I, Nakata K, Sasaki A, Miyamoto T, Ikekita M. Induction of mitochondria-involved apoptosis in estrogen receptor-negative cells by a novel tamoxifen derivative, ridaifen-B. Cancer Sci. 2008 Mar;99(3):608-14. doi: 10.1111/j.1349-7006.2007.00709.x. Epub 2007 Dec 19. PubMed PMID: 18167132.