| Description | Riboxin (IDP), an orally administered purine derivative known as hypoxanthine riboside, exhibits antihypoxic and antihyperthermic effects. Furthermore, it demonstrates antiarrhythmic properties in cats, rabbits, and mice suffering from Ouabain-induced cardiac rhythm abnormalities. Additionally, Riboxin offers protection to animals from the harmful consequences of γ-irradiation [1] [2]. |
| In vivo | Riboxin（250 mg/kg；口服；单剂量）能延长小鼠的游泳耐力，但力量耐力未见明显改善。在相同剂量下，能提升热室试验中的小鼠存活率[1]。每日一次连续六日给予Riboxin（50 mg/kg；口服）后，小鼠的活动时间延长，但游泳及跑步能力未受显著影响[1]。给药前一小时，Riboxin（250 mg/kg；口服）对小鼠提供了显著的γ辐射保护[1]。 |
| Synonyms | IDP |
| molecular weight | 428.19 |
| Molecular formula | C10H14N4O11P2 |
| CAS | 86-04-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |