| Description | Rhaponticin 6''-O-gallate showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM). |
| In vitro | Two new anthraquinone glucosides [chrysophanol 8-O-beta-D-(6'-galloyl)-glucopyranoside, aloe-emodin 1-O-beta-D-glucopyranoside] together with various known stilbenes and their glucosides, anthraquinone glucosides, and a naphthalene glucoside were isolated from the rhizome of Rheum undulatum L. Three stilbenes (rhapontigenin, piceatannol, resveratrol), a naphthalene glucoside (torachrysone 8-O-beta-D-glucopyranoside), and two stilbene glucoside gallates (rhaponticin 2''-O-gallate, Rhaponticin 6''-O-gallate) showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM). |
| Synonyms | 土大黄苷 6''-O-没食子酸酯, Rhaponticin 6''-O-gallate |
| molecular weight | 572.51 |
| Molecular formula | C28H28O13 |
| CAS | 94356-23-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages.Bioorg Med Chem Lett. 2000 Feb 21;10(4):323-7. |