| Description | RG 6866 is a inhibitor of 5-lipoxygenase. |
| Synonyms | RG-6866, RG6866 |
| molecular weight | 271.31 |
| Molecular formula | C16H17NO3 |
| CAS | 120602-97-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Gleason MM, Rojas CJ, Learn KS, Perrone MH, Bilder GE. Characterization and inhibition of 15-lipoxygenase in human monocytes: comparison with soybean 15-lipoxygenase. Am J Physiol. 1995 May;268(5 Pt 1):C1301-7. PubMed PMID: 7762624. 2. Folcik VA, Cathcart MK. Assessment of 5-lipoxygenase involvement in human monocyte-mediated LDL oxidation. J Lipid Res. 1993 Jan;34(1):69-79. PubMed PMID: 8445344. 3. Derian CK, Lewis DF. Activation of 15-lipoxygenase by low density lipoprotein in vascular endothelial cells. Relationship to the oxidative modification of low density lipoprotein. Prostaglandins Leukot Essent Fatty Acids. 1992 Jan;45(1):49-57. PubMed PMID: 1546066. 4. Snyder DW, Cho HL, Gilmore J. Endogenously formed leukotriene C4 activates LTC4 receptors in guinea pig tracheal strips. Eur J Pharmacol. 1991 Mar 26;195(2):209-15. PubMed PMID: 1651863. |