| Description | Regorafenib (BAY 73-4506) mesylate is an orally active multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1/2/3 (IC50=13/4.2/46 nM), PDGFRβ (IC50: 22 nM), Kit (IC50: 7 nM), RET (IC50: 1.5 nM) and Raf-1 (IC50: 2.5 nM). Regorafenib mesylate has potent anti-tumour and anti-angiogenic effects. |
| molecular weight | 578.92 |
| Molecular formula | C22H19ClF4N4O6S |
| CAS | 835621-08-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |