Description | Rbin-1 (Ribozinoindole-1) is a potent,specific inhibitor of eukaryotic ribosome biogenesis. |
Target activity | ATPase:136±7 nM (GI50) |
Synonyms | Ribozinoindole-1 |
molecular weight | 256.33 |
Molecular formula | C13H12N4S |
CAS | 328023-11-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 31 mg/mL (120.94 mM) |
References | 1. Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis. 2. Kawashima S , Chen Z , Aoi Y , et al. Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis[J]. Cell, 2016:S0092867416311680. |