| Description | 1. Raspberry ketone (p-Hydroxybenzyl acetone) is cytotoxic to melanocytes through the binding of RK-derived quinones to thiol proteins and the pro-oxidant activity of the RK-oligomer, the exposure of human skin to RK can cause chemical/occupational leukoderma. 2. Raspberry ketone is marketed on the Internet as a food supplement. |
| Synonyms | Oxyphenalon, Rasketone, Aloenin, 4-(4-Hydroxyphenyl)-2-butanone, p-Hydroxybenzyl acetone, Frambinone, 覆盆子酮 |
| molecular weight | 164.2 |
| Molecular formula | C10H12O2 |
| CAS | 5471-51-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (365.41 mM) |
| References | 1. Ito S, Hinoshita M, Suzuki E, et al. The Tyrosinase-Catalyzed Oxidation of the Leukoderma-inducing Agent Raspberry Ketone Produces (E)-4-(3-oxo-1-butenyl)-1,2-benzoquinone: Implications for Melanocyte Toxicity[J]. Chemical Research in Toxicology, 2017, 30(3):859. |