| Description | Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells). |
| Synonyms | AY-22989-d3, Sirolimus-d3 |
| molecular weight | 917.19 |
| Molecular formula | C51H79NO13 |
| CAS | 392711-19-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Edwards SR, et al. The rapamycin-binding domain of the protein kinase mammalian target of rapamycin is a destabilizing domain. J Biol Chem, 2007, 282(18), 13395-13401. 2. Rangaraju S, et al. Rapamycin activates autophagy and improves myelination in explant cultures from neuropathicmice. J Neurosci. 2010 Aug 25;30(34):11388-97. |