| Description | (R)-VU 6008667 is devoid of M5 NAM activity (IC50>10 μM). |
| molecular weight | 438.85 |
| Molecular formula | C24H17ClF2N2O2 |
| CAS | 2097818-14-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 100 mg/mL (227.87 mM), Sonication is recommended. |
| References | 1. McGowan KM et al, Continued optimization of the M5 NAM ML375: Discovery of VU6008667, an M5 NAM with high CNS penetration and a desired short half-life in rat for addiction studies. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1356-1359. |