| Description | Quinidine hydrochloride monohydrate is an optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. It prolongs cellular action potential and decreases automaticity. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission. |
| Target activity | K+ channel:19.9 μM |
| Synonyms | 奎宁树, 奎尼丁盐酸盐一水合物, 奎尼丁盐酸盐, Quinidine hydrochloride |
| molecular weight | 378.89 |
| Molecular formula | C20H27ClN2O3 |
| CAS | 6151-40-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 32.5 mg/mL (85.77 mM) |
| References | 1. Stokoe KS, et al. J Physiol. 2007 Jan 1;578(Pt 1):69-84. |
Quinidine hydrochloride monohydrate
CAS No.: 6151-40-2
Quinidine hydrochloride monohydrate is an optical isomer of quinine, extracted from the bark of the Cinchona tree and si
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