| Description | Quadrosilan is a synthetic, nonsteroidal estrogen. |
| Synonyms | KABI1774, KABI 1774, KABI-1774, Cisobitan |
| molecular weight | 420.75 |
| Molecular formula | C18H28O4Si4 |
| CAS | 4657-20-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Alfthan O, Andersson L, Esposti PL, Fosså SD, Gammelgaard PA, Gjöres JE, Isacson S, Rasmussen F, Ruutu M, von Schreeb T, Setterberg G, Strandell P, Strindberg B. Cisobitan in treatment of prostatic cancer. A prospective controlled multicentre study. Scand J Urol Nephrol. 1983;17(1):37-43. PubMed PMID: 6346476. 2. Collste L, Berlin T, von Garrelts B, Granberg I, Lewander R. Clinical trial of a new antigonadotropic substance, 2,6-cis-diphenylhexamethylcyclotetrasiloxane, in cancer of the prostate. A pilot study. Eur Urol. 1981;7(2):85-8. PubMed PMID: 7461008. 3. Sundwall A. Cisobitan--a new drug with anti-gonadotropic and anti-androgenic properties. Pharmacological effects. Scand J Urol Nephrol Suppl. 1980;55:121-5. PubMed PMID: 6938014. 4. Albanus L, Björklund NE, Gustafsson B, Jönsson M. Forty days oral toxicity of 2,6-cis-diphenylhexamethylcyclotetrasiloxane (KABI 1774)in beagle dogs with special reference to effects on the male reproductive system. Acta Pharmacol Toxicol (Copenh). 1975;36(Suppl 3):93-130. PubMed PMID: 1080338. |