| Description | QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40. Additionally, QR-0217 has been shown to alleviate memory impairments attributed to Aβ neurotoxicity [1]. |
| In vitro | QR-0217（20、100 µM；96小时）可抑制α-突触核蛋白（4 μM）的聚集[1]。同一化合物在50 µM浓度显著恢复了APP/PS1转基因小鼠海马切片中受损的LTP[1]。 |
| molecular weight | 303.31 |
| Molecular formula | C19H13NO3 |
| CAS | 1027786-12-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |