| Description | Pyruvate Carboxylase-IN-1 (compound 37), a natural analog of erianin, is a potent inhibitor of pyruvate carboxylase (PC), exhibiting inhibitory concentrations (IC50) of 0.204 μM and 0.104 μM in cell lysate-based and cell-based PC activity assays, respectively. This compound effectively inhibits PC enzymatic activity, contributing to its anticancer effects in human hepatocellular carcinoma (HCC) [1]. |
| molecular weight | 242.27 |
| Molecular formula | C15H14O3 |
| CAS | 70205-50-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |