| Description | PT-S58 is a PPAR β/δ full antagonist, and a derivative of GSK0660. PT-S58 has a three-fold higher affinity for the receptor than GSK0660 and is a potent inhibitor of agonist-induced target gene expression. PT-S58 are effective on PPRE-independent functions of PPARβ/δ. Unlike GSK0660, PT-S58 blocks the recruitment co-repressor molecules such as SMRT. |
| molecular weight | 398.5 |
| Molecular formula | C17H22N2O5S2 |
| CAS | 1356497-92-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |