PeptideDB

PS121912

CAS No.: 1529814-60-5

PS121912 is a potent and selective inhibitor of VDR-coactivator.
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Description PS121912 is a potent and selective inhibitor of VDR-coactivator.
Synonyms PS-121912, PS 121912
molecular weight 410.43
Molecular formula C24H21F3N2O
CAS 1529814-60-5
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Guthrie ML, Sidhu PS, Hill EK, Horan TC, Nandhikonda P, Teske KA, Yuan NY, Sidorko M, Rodali R, Cook JM, Han L, Silvaggi NR, Bikle DD, Moore RG, Singh RK, Arnold LA. Antitumor Activity of 3-Indolylmethanamines 31B and PS121912. Anticancer Res. 2015 Nov;35(11):6001-7. PubMed PMID: 26504023; PubMed Central PMCID: PMC4633305. 2. Sidhu PS, Teske K, Feleke B, Yuan NY, Guthrie ML, Fernstrum GB, Vyas ND, Han L, Preston J, Bogart JW, Silvaggi NR, Cook JM, Singh RK, Bikle DD, Arnold LA. Anticancer activity of VDR-coregulator inhibitor PS121912. Cancer Chemother Pharmacol. 2014 Oct;74(4):787-98. doi: 10.1007/s00280-014-2549-y. Epub 2014 Aug 9. PubMed PMID: 25107568; PubMed Central PMCID: PMC4177010. 3. Sidhu PS, Nassif N, McCallum MM, Teske K, Feleke B, Yuan NY, Nandhikonda P, Cook JM, Singh RK, Bikle DD, Arnold LA. Development of novel Vitamin D Receptor-Coactivator Inhibitors. ACS Med Chem Lett. 2014 Feb 13;5(2):199-204. PubMed PMID: 24799995; PubMed Central PMCID: PMC4007349.