| Description | Propargyl-PEG4-tetra-Ac-beta-D-galactose is a PEGylated proteolysis-targeting chimera (PROTAC) linker utilized for PROTAC synthesis[1]. |
| In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| molecular weight | 562.56 |
| Molecular formula | C25H38O14 |
| CAS | 1397682-61-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
Propargyl-PEG4-tetra-Ac-beta-D-galactose
CAS No.: 1397682-61-9
Propargyl-PEG4-tetra-Ac-beta-D-galactose is a PEGylated proteolysis-targeting chimera (PROTAC) linker utilized for PROTA
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