| Description | Prodan, a solvatochromic fluorophore, serves as a sensitive reporter for microenvironment changes in membranes. Utilizing Prodan's chemistry, researchers have designed and synthesized fluorescent nucleosides that exhibit a sensitive variation in their Stokes shift values, reflecting the orientational polarizability of the solvent. |
| molecular weight | 227.3 |
| Molecular formula | C15H17NO |
| CAS | 70504-01-7 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMF: 10 mg/mL DMSO: 5 mg/mL DMF:PBS (pH 7.2) (1:2): 0.3 mg/mL Ethanol: 1 mg/mL |
| References | 1. Kucherak, O.A., Didier, P., Mély, Y., et al. Fluorene analogues of prodan with superior fluorescence brightness and solvatochromism. J. Phys. Chem. Lett. 1(3), 616-620 (2010). 2. Parasassi, T., Krasnowska, E.K., Bagatolli, L., et al. Laurdan and prodan as polarity-sensitive fluorescent membrane probes. J. Fluoresc. 8(4), 365-373 (1998). 3. Mennucci, B., Caricato, M., Ingrosso, F., et al. How the environment controls absorption and fluorescence spectra of PRODAN: A quantum-mechanical study in homogeneous and heterogeneous media. J. Phys. Chem. B 112(2), 414-423 (2008). |