| Description | Pritumumab, a natural human IgG1kappa monoclonal antibody (mAb), was first isolated from the regional draining lymph node of a cervical carcinoma patient. It specifically recognizes cell-surface-expressed vimentin on malignant tumors and has applications in glioblastoma research [1] [2]. |
| In vivo | Pritumumab 在裸鼠体内能有效抑制肿瘤生长，然而在SCID小鼠中效果不彰[1]。Pritumumab 的抗肿瘤效果依赖于完整的细胞介导免疫反应，仅在此环境下才能有效限制异种移植胶质瘤肿瘤生长[1]。 |
| molecular weight | N/A |
| CAS | 499212-74-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 years |