Description | Pristane (2,6,10,14-tetramethylpentadecane) is a natural product from shark liver oil and a non-antigenic adjuvant. |
In vivo | 在天真接受者大鼠(DA)中,经皮内注射500μL Pristane油后,直至注射后第6天,CD4+、CD8+ αβT细胞和B细胞在引流淋巴结中显著扩增,之后CD4+ αβT细胞持续扩增直至注射后第12天[2]。 |
Synonyms | 姥鲛烷, 2,6,10,14-tetramethylpentadecane |
molecular weight | 268.52 |
Molecular formula | C19H40 |
CAS | 1921-70-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 80.56 mg/mL (300 mM), Sonication is recommended. |
References | 1. J J Turner, et al. Krypton Fluoride: Preparation by the Matrix Isolation Technique. Science. 1963 May 31;140(3570):974-5. 2. Jens Holmberg,et al. Pristane, a non-antigenic adjuvant, induces MHC class II-restricted, arthritogenic T cells in the rat. J Immunol. 2006 Jan 15;176(2):1172-9. 3. Satoh M, Richards HB, Shaheen VM, Yoshida H, Shaw M, Naim JO, Wooley PH, Reeves WH. Widespread susceptibility among inbred mouse strains to the induction of lupus autoantibodies by pristane. Clin Exp Immunol. 2000 Aug;121(2):399-405. |