| Description | Prifelone (R 830) is a non-steroidal anti-inflammatory compound with antioxidant activity. |
| In vitro | R-830 以浓度相关的方式抑制了豚鼠肺部的脂氧合酶，其大约IC50值为2 x 10^-5 M。[1] 同时，R-830 在0.5%的浓度下抑制了花生油的自动氧化作用。[1] |
| In vivo | R-830（0.3-20 mg/kg），一种二叔丁基苯酚，在减少已有后腿肿胀及促进体重增加方面显示出剂量反应效果，取得了疗效。[1] |
| Synonyms | R-830, R830, S-16820, S 16820, R 830 |
| molecular weight | 316.46 |
| Molecular formula | C19H24O2S |
| CAS | 69425-13-4 |
| Storage | |Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (173.8 mM) |
| References | 1. Moore GG, et al. 2,6-Di-tert-butyl-4-(2'-thenoyl)phenol(R-830): a novel nonsteroidal anti-inflammatory agent with antioxidant properties. Agents Actions. 1982;12(5-6):674-683. 2. Braun S, et al. Synthesis and In Vitro Biological Evaluation of p-Carborane-Based Di-tert-butylphenol Analogs. Molecules. 2023;28(11):4547. |