| Description | Preq1-Dihydrochloride (pre-queuosine1 Dihydrochloride) is an intermediate of the queuosine pathway, it binds with high affinity to the aptamer of PreQ1 riboswitch, which attenuates protein expression. |
| Synonyms | pre-queuosine1 Dihydrochloride |
| molecular weight | 252.1 |
| Molecular formula | C7H11Cl2N5O |
| CAS | 86694-45-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 10 mg/mL（39.67 mM）, Sonication is recommended. |
| References | 1. Vlack E V , Topp S , Seeliger J C , et al. Characterization of Engineered PreQ1 Riboswitches for Inducible Gene Regulation in Mycobacteria[J]. Journal of Bacteriology, 2017, 199(6):e00656-16. |