| Description | Pravastatin lactone is a metabolite of pravastatin , a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor that is a ring-hydroxylated metabolite of mevastatin . Pravastatin lactone is formed when pravastatin undergoes acid-catalyzed non-enzymatic lactonization in the stomach following oral administration. |
| molecular weight | 406.519 |
| Molecular formula | C23H34O6 |
| CAS | 85956-22-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 20 mg/mL DMF: 25 mg/mL PBS (pH 7.2): 10 mg/mL Ethanol: 12.5 mg/mL |