| Description | Prajmalium bitartrate, a derivative of the rauwolfia alkaloid AJMALINE, is an anti-arrhythmia agent but may cause liver damage. |
| Synonyms | Neo-gilurytmal, NPAP |
| molecular weight | 518.607 |
| Molecular formula | C27H38N2O8 |
| CAS | 2589-47-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Trefanec J, Langmeierová M, Zelezná J. [Acute anicteric hepatitis and intrahepatic cholestasis caused by administration of prajmalium bitartrate (Neo-Gilurytmal)]. Cas Lek Cesk. 1994 Jan 31;133(3):83-5. Czech. PubMed PMID: 8137378. 2. Breuel HP, Weimann HJ, Dahmen W, Hausleiter HJ, Bondy S. Pharmacokinetics and relative bioavailability of prajmalium bitartrate after single oral dosing. Arzneimittelforschung. 1991 Dec;41(12):1222-5. PubMed PMID: 1815520. 3. Jähnchen E. [Interactions between digitoxin, flecainide and prajmalium bitartrate?]. Dtsch Med Wochenschr. 1991 Jun 28;116(26):1035-6. German. PubMed PMID: 1905622. 4. Azzam Z, Krivoy N. [Transient liver damage due to prajmalium bitartrate]. Harefuah. 1991 Jan 1;120(1):17-8. Hebrew. PubMed PMID: 2010122. |