PeptideDB

PPZ2

CAS No.: 896203-18-2

PPZ2 is a novel DAG-activated TRPC3/TRPC6/TRPC7 channels activator.
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Description PPZ2 is a novel DAG-activated TRPC3/TRPC6/TRPC7 channels activator.
Synonyms PPZ-2, PPZ 2
molecular weight 367.48
Molecular formula C22H29N3O2
CAS 896203-18-2
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Sawamura S, Hatano M, Takada Y, Hino K, Kawamura T, Tanikawa J, Nakagawa H, Hase H, Nakao A, Hirano M, Rotrattanadumrong R, Kiyonaka S, Mori MX, Nishida M, Hu Y, Inoue R, Nagata R, Mori Y. Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds. Mol Pharmacol. 2016 Mar;89(3):348-63. doi: 10.1124/mol.115.102863. Epub 2016 Jan 5. PubMed PMID: 26733543. 2. Cheng YL, Chen RH. Assembly and quality control of the protein phosphatase 1 holoenzyme involves the Cdc48-Shp1 chaperone. J Cell Sci. 2015 Mar 15;128(6):1180-92. doi: 10.1242/jcs.165159. Epub 2015 Jan 22. PubMed PMID: 25616896. 3. Merchan S, Pedelini L, Hueso G, Calzada A, Serrano R, Yenush L. Genetic alterations leading to increases in internal potassium concentrations are detrimental for DNA integrity in Saccharomyces cerevisiae. Genes Cells. 2011 Feb;16(2):152-65. doi: 10.1111/j.1365-2443.2010.01472.x. Epub 2010 Dec 9. PubMed PMID: 21143561. 4. Bozaquel-Morais BL, Madeira JB, Maya-Monteiro CM, Masuda CA, Montero-Lomeli M. A new fluorescence-based method identifies protein phosphatases regulating lipid droplet metabolism. PLoS One. 2010 Oct 28;5(10):e13692. doi: 10.1371/journal.pone.0013692. PubMed PMID: 21060891; PubMed Central PMCID: PMC2965658.