| Description | POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration. |
| In vitro | POT-4 acetate（一种compstatin衍生物），通过与C3结合从而阻止其分裂成活性片段C3a和C3b[1]。 |
| Synonyms | POT-4 acetate (934461-40-2 free base) |
| molecular weight | 1687.9 |
| Molecular formula | C74H106N22O20S2 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Robyn Troutbeck, et al. Therapeutic targeting of the complement system in age-related macular degeneration: a review. Clin Exp Ophthalmol. Jan-Feb 2012;40(1):18-26. 2. S. Kaushal, et al. Complement C3 inhibitor POT-4: Clinical Safety of Intravitreal Administration. ARVO Annual Meeting Abstract, 2009 Apr. |