| Description | Porfiromycin is a n N-methyl derivative of the antineoplastic antibiotic mitomycin C isolated from the bacterium Streptomyces ardus and other Streptomyces bacterial species. Bioreduced porfiromycin generates oxygen radicals and alkylates DNA, producing interstrand cross-links and single-strand breaks, thereby inhibiting DNA synthesis. Porfiromycin is preferentially toxic to hypoxic cells. |
| molecular weight | 348.35 |
| Molecular formula | C16H20N4O5 |
| CAS | 801-52-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |