| Description | Ponasterone A is an ecdysteroid with high affinity for the ecdysteroid receptor. It enables rapid switching on and off of reporter genes and is a potent regulator of gene expression in cells and transgenic animals. |
| In vitro | Ponasterone A 在 CV-1 细胞中展示了显著的基因诱导活性[2]。 |
| In vivo | Ponasterone A 在 Transactivator 和 reporter mice[2] 中强烈诱导基因表达。 |
| Synonyms | 坡那甾酮A, AI3-44686 |
| molecular weight | 464.63 |
| Molecular formula | C27H44O6 |
| CAS | 13408-56-5 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: Soluble |
| References | 1. Kine H , Johan I , Eirin G , et al. Ponasterone A and F, Ecdysteroids from the Arctic Bryozoan Alcyonidium gelatinosum[J]. Molecules, 2018, 23(6):1481-. 2. Gu, Y. Evidence That Collapsin Response Mediator Protein-2 Is Involved in the Dynamics of Microtubules[J]. Journal of Biological Chemistry, 2000, 275(24):17917-20. |