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Pom-8PEG

CAS No.: 2488761-03-9

Pom-8PEG is an E3 ubiquitin ligase ligand-linker conjugate consisting of a cereblon (CRBN) ligand and an 8-unit PEG link
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Description Pom-8PEG is an E3 ubiquitin ligase ligand-linker conjugate consisting of a cereblon (CRBN) ligand and an 8-unit PEG linker. This compound can be utilized for the synthesis of PROTAC, including the IDO1 PROTAC degrader.
molecular weight 625.672
Molecular formula C29H43N3O12
CAS 2488761-03-9
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Hu M, et al. Discovery of the first potent proteolysis targeting chimera (PROTAC) degrader of indoleamine 2,3-dioxygenase 1. Acta Pharm Sin B. 2020;10(10):1943-1953.