| Description | Polyketide synthase 13-IN-3 (compound 41) is a potent inhibitor of polyketide synthase 13, demonstrating a minimum inhibitory concentration (MIC) range of 0.0625-0.125 μg/mL against the M. tuberculosis strain H37Rv. |
| Target activity | M. tuberculosis (strain H37Rv):0.0625-0.125 μg/mL (MIC) |
| molecular weight | 349.386 |
| Molecular formula | C21H19NO4 |
| CAS | 2221801-50-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Wei Zhang, et al. Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II. J Med Chem. 2019 Apr 11;62(7):3575-3589. |