| Description | Platycoside G1 (Deapi-platycoside E) may have anti-inflammatory effects. |
| In vitro | 通过使用HPLC结合蒸发光散射检测（ELSD）系统，研究了经过1、2、3、6及9小时加热处理后的桔梗根中platycoside成分的变化。经过125°C加热处理（1、2、3、6及9小时后），多种platycoside如platycoside E、 platycodin D3、platycodin D、polygalacin D及platycodin A的含量随处理时间增长而减少。尽管总皂苷含量降低，但Deapi-platycoside E、deapi-platycodin D3及deapi-platycodin D的deapi形式含量相对增加。这些结果表明，位于C-28的apiose和xylose之间的连接对热和压力敏感。经过1和2小时处理的样品显示出增强的LPS诱导的iNOS抑制活性，之后活性降低。 |
| Synonyms | 桔梗皂苷G1, Deapi-platycoside E |
| molecular weight | 1417.49 |
| Molecular formula | C64H104O34 |
| CAS | 849758-42-5 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 75 mg/mL (52.91 mM) |
| References | 1. Compositional analysis of major saponins and anti-inflammatory activitiy of steam-processed platycodi radix under pressure. Natural Product Sciences, 2008, 14(4):274-280. |
| Citations | 1. Lee S J, Kim H W, Lee S, et al. Characterization of Saponins from Various Parts of Platycodon grandiflorum Using UPLC-QToF/MS. Molecules. 2022, 27(1): 107. |