| Description | Pirozadil shows hypolipidemic activity. |
| In vivo | 经过3个月的Pirozadil治疗后，观察到显著的血浆胆固醇从299.8 +/- 31.2 mg/dl降至256.8 mg/dl，以及低密度脂蛋白(LDL)胆固醇从211.7 mg/dl降至168.8 mg/dl。高密度脂蛋白(HDL)胆固醇未见变化。该化合物耐受性好，未观察到副作用。 |
| molecular weight | 527.52 |
| Molecular formula | C27H29NO10 |
| CAS | 54110-25-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: Insoluble DMSO: 13.75 mg/mL (26.07 mM), Sonication is recommended. |
| References | 1. Masana L, et al. Treatment of diet-resistant polygenic hypercholesterolaemic patients with a new nicotinate derivative; in vivo and in vitro low density lipoprotein metabolic studies. J Clin Pharmacol. 1989 Mar;29(3):201-6. |