| Description | Pipoxizine has an antagonistic effect on histamine-induced bronchoconstriction and may be used in the study of asthma disease. |
| In vivo | Pipoxizine 通过口服方式给予10名患者,另外10名则通过静脉注射给药。结果的统计分析显示,Pipoxizine 对组胺引起的支气管收缩具有拮抗作用。[1] |
| molecular weight | 381.51 |
| Molecular formula | C24H31NO3 |
| CAS | 55837-21-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 45 mg/mL (117.95 mM) |
| References | 1. Neukirch F, et al. Effect of a histamine aerosol in 20 subjects with histamine hyperreactivity. Application to a study of the protective properties of pipoxizine. Rev Inst Hyg Mines (Hasselt). 1978;33(4):191-195. 2. Verstraeten JM. Double blind cross over study with pipoxizine and fenoterol given orally on cord patients (author's transl). Acta Tuberc Pneumol Belg. 1978;69(3-4):247-255. |