| Description | Piperphentonamine HCL is a potential calcium sensitizer for the treatment of heart failure. |
| Synonyms | PPTA |
| molecular weight | 389.88 |
| Molecular formula | C21H24ClNO4 |
| CAS | 136467-36-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Shi A, Hu X, Li K, Li J, Han L, Wan H, Li R. Determination of piperphentonamine and metabolites M1 and M6 in human plasma and urine by LC/MS/MS and its application in a pharmacokinetics study in Chinese healthy volunteers. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Nov 1;908:87-93. doi: 10.1016/j.jchromb.2012.09.031. PubMed PMID: 23122405. 2. Bin J, Wang Q, Zhuo YY, Xu JP, Zhang HT. Piperphentonamine (PPTA) attenuated cerebral ischemia-induced memory deficits via neuroprotection associated with anti-apoptotic activity. Metab Brain Dis. 2012 Dec;27(4):495-505. doi: 10.1007/s11011-012-9330-x. PubMed PMID: 22843383. 3. Li Y, Li W, Wu J, Chen H, Wan L. [Effect of piperphentonamine hydrochloride on expressions of interleukin-1β and TNF-α mRNA and Fas protein in guinea pigs with cochlear ischemia/reperfusion injury]. Nan Fang Yi Ke Da Xue Xue Bao. 2013 Nov;33(11):1669-72. Chinese. PubMed PMID: 24273275. 4. Zhu HY, Bin J, Wang C, Lin HB, Zhou H, Xu JP. [Effects of piperphentonamine hydrochloride on cognitive deficits in rats induced by cerebral ischemia-reperfusion]. Nan Fang Yi Ke Da Xue Xue Bao. 2011 Nov;31(11):1858-62. Chinese. PubMed PMID: 22126765. |