| Description | PI3Kδ-IN-14 (Compound (S)-29), a selective PI3Kδ inhibitor with an IC50 of 0.8 nM and a Kd of 84.8 nM, targets the ATP-binding site within the kinase domain of PI3Kδ. This compound exhibits anti-inflammatory properties by impeding the PI3K/AKT pathway and is noted for alleviating acute lung injury (ALI) [1]. |
| molecular weight | 514.94 |
| Molecular formula | C26H20ClFN8O |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |